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Uridine triphosphate

CAS No. 63-39-8

Uridine triphosphate( UTP | Uridine 5'-triphosphate )

Catalog No. M20977 CAS No. 63-39-8

Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Uridine triphosphate
  • Note
    Research use only, not for human use.
  • Brief Description
    Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.
  • Description
    Uridine triphosphate increases proliferation of human cancerous pancreatic duct epithelial cells by activating P2Y2 receptor.
  • In Vitro
    Western Blot Analysis Cell Line:RT4-D6P2T cells Concentration:250 μM Incubation Time:5 min, 45 min, 2 h, 6 h, 12 h, 24 h, 48 h Result:Induces biphasic MAPK phosphorylation.
  • In Vivo
    Animal Model:Male Wistar rats (250-300 g; 2-3 months) with myocardial infarction (MI)Dosage:0.44 μg/kg 30 min before MI, and 4.4 μg/kg i.v. 24 h prior to MI.Administration:i.v.; once Result:Reduced infarct size and improves rat heart function after myocardial infarct.
  • Synonyms
    UTP | Uridine 5'-triphosphate
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    Metabolic Disease
  • Indication
    Bronchitis; Cystic fibrosis; Lung Cancer; Primary ciliary dyskinesia

Chemical Information

  • CAS Number
    63-39-8
  • Formula Weight
    484.14
  • Molecular Formula
    C9H15N2O15P3
  • Purity
    >98% (HPLC)
  • Solubility
    H2O:150 mg/mL (309.83 mM)
  • SMILES
    O=c1ccn(C2OC(COP(=O)(O)OP(=O)(O)OP(=O)(O)O)C(O)C2O)c(=O)[nH]1
  • Chemical Name
    (((2R3S4R5R)-5-(24-dioxo-34-dihydropyrimidin-1(2H)-yl)-34-dihydroxytetrahydrofuran-2-yl)methyl)triphosphoric acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Choi J H Ji Y G Lee D H . Uridine Triphosphate Increases Proliferation of Human Cancerous Pancreatic Duct Epithelial Cells by Activating P2Y2 Receptor[J]. Pancreas 2013 42(4):680-686.
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